What you know about Acetylsalicylic acid

Aspirin, is referred to acetylsalicylic acid. Acetylsalicylic acid is the world's most widely used drugs. Acetylsalicylic acid is a white, crystalline composition, Pickle. It is usually mixed with other drugs. Acetylsalicylic acid can relieve mild to moderate pain: headache, backache, toothaches, and muscle pain. It can relieve arthritis and rheumatic fever burning in the swelling; it can bring down a fever. Daily in small doses, it can reduce the incidence of heart disease and other small stroke risk factor.

Acetylsalicylic acid(CAS NO: 50-78-2 ) can interfere with the generation of prostaglandins, prostaglandins are hormonal substances, can produce heat, intensified redness, increased sensitivity to pain nerves. Acetylsalicylic acid can prevent blood clots; blood clots are made of prostaglandins. This explains why Acetylsalicylic acid can help relieve pain in patients with heart disease, patients suffering from internal bleeding problems but can not take Acetylsalicylic acid.

For many people Acetylsalicylic acid has side effects: heartburn, indigestion, nausea and vomiting. Acetylsalicylic acid can irritate the stomach membrane, can cause internal bleeding. Allergic reactions include abdominal pain, itching, swelling of the face and throat. Long-term use can cause iron deficiency, stomach ulcers and gastrointestinal bleeding.

Acetylsalicylic acid should be placed on the reach of children, according to the doctor's orders for them to take. Acetylsalicylic acid can not give the age of 18 infected with the virus, such as influenza and varicella (chickenpox), the kids take. Children suffering from these diseases if taking Acetylsalicylic acid can cause severe Reye syndrome.

Acetylsalicylic acid in tablets, capsules, chewable tablets and suppositories form for sale. The efficacy of Acetylsalicylic acid by time release capsule can slowly release the drug within a few hours, which Acetylsalicylic acid is generally used to treat arthritis. Result of taking Acetylsalicylic acid and abdominal pain that people can use two special Acetylsalicylic acid, called buffered Acetylsalicylic acid (buffered Acetylsalicylic acid), medicine contains antacids; another called enteric Acetylsalicylic acid (enteric-coated Acetylsalicylic acid), which Acetylsalicylic acid coat is resistant to acid corrosion, only to the small intestine will begin to release the drug. Acetylsalicylic acid should take water, such as and other fluids taken together, like fruit juices and alcoholic beverages, can easily irritate the stomach.

Acetylsalicylic acid substitutes include acetyl amino benzene (acetaminophen) and ibuprofen (ibuprofen). These two drugs are specifically caused as a result of taking Acetylsalicylic acid allergy and gastrointestinal discomfort for people and production. Acetyl amino benzene (Acetaminophen) compared with Acetylsalicylic acid and ibuprofen, can bring fewer side effects and allergic reactions. However, before taking the two drugs should also consult a physician, because these two drugs in patients with certain diseases would have a negative effect.

Acetylsalicylic acid belongs to a class called salicylates compound, this compound in the plant where it is. 400 BC Hippocrates (Hippocrates, 460 BC to 360 doctors of ancient Greece, the Bank said the father of medicine), have used willow bark to relieve pain, willow bark contains salicylates compounds. In 1853, Charles • Where • Gerhardt (Charles von Gerhardt, German chemist) was first synthesized acetylsalicylic acid (acetylsalicylic acid). In 1893, Felix Hoffman, another German doctor, discovered with the lowest cost method of mass production of this drug. In 1899, this drug was first to begin selling the name Acetylsalicylic acid. Acetylsalicylic acid has been trademark, until 1921 the court declared Acetylsalicylic acid is acetylsalicylic acid name drugs, because it has been so widely used.

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An interesting story about Acetylsalicylic acid

Acetylsalicylic Acid, also known by trade name Aspirin, is an acetyl derivative of salicylic acid that is a white, crystalline, weakly acidic substance, with melting point 137°C. Its CAS NO is 50-78-2.

Today, Acetylsalicylic Acid is one of the most widely used medications in the world, estimated 40,000 tones of Acetylsalicylic Acid being consumed each year. In countries where Acetylsalicylic Acid is a registered trademark owned by Bayer, the generic term is acetylsalicylic acid (ASA).

      

Today, most of us well know of Acetylsalicylic Acid, but you may not hear about the history of Acetylsalicylic Acid. The origin of Acetylsalicylic Acid has a long history; this article will give you the answer.

In 2300 years ago, the founder of Western medicine, the Greek physiological and medical scientist F Pokela Di has found, water willow leaf and leather goods has analgesic and antipyretic effect, but he didn’t clear its active ingredients then.

In 1827, British scientists first discovered LAROX willow contains a substance called salicin. In 1853, the German chemist Jerg first synthetic salicylates predecessor -- Pure salicylic acid, it has antipyretic analgesic effect, but highly toxic, has strong stimulation to the stomach. In 1897, another German chemist Hoffman, for relieving his father’s rheumatic pain, he changed the pure salicylic acid to acetylsalicylic acid.

Since then, the acetylsalicylic acid has been recognized by public, and it was gradually used down, which is now known as Acetylsalicylic Acid. It remains the properties of pure salicylic acid, but its toxicity and adverse reaction was greatly reduced.

Because Acetylsalicylic Acid has magical effect on the fever, the demand for Acetylsalicylic Acid is huge. Very soon, the German chemist Bayer founded the manufacturing process with industrial methods of Acetylsalicylic Acid in 1899, started mass production of Acetylsalicylic Acid, and sell well all over the world.

China began production Acetylsalicylic Acid in 1958. Now, Acetylsalicylic Acid has been used for hundreds of years, it becomes one of the three major classical drugs in history of medicine.

It remains most widely used for antipyretic, analgesic and anti-inflammatory in the world. Acetylsalicylic Acid is always used as the comparison and evaluation of standard preparation of other drugs. The medicine can be used for antipyretic analgesic and anti-inflammatory (fever, toothache, pain, acute rheumatic fever, diagnosis and differential diagnosis of rheumatic and rheumatoid arthritis).

Frankie is the freelance writer for e-commerce website in the chemistry. Guidechem.com is just a place for you to look for some chemicals. Our guidechem provide the most convenient conditions for the international buyers and let these leads benefit all the business people. Guidechem chemical B2B network provides information on china and global chemical market quotation and relative chemical Information. Guidechem Chemical Network providing the most complete information of the chemical industry.

Acetylsalicylic acid’s significant role in medical community

Acetylsalicylic Acid, also known by trade name Aspirin, is an acetyl derivative of salicylic acid that is a white, crystalline, weakly acidic substance, with melting point 137°C. Its CAS NO is 50-78-2.

Today, aspirin is one of the most widely used medications in the world, with an estimated 40,000 tonnes of it being consumed each year. In countries where Aspirin is a registered trademark owned by Bayer, the generic term is acetylsalicylic acid (ASA).

Acetylsalicylic acid is useful in the relief of headache and muscle and joint aches. Aspirin is also effective in reducing fever, inflammation, and swelling and thus has been used for treatment of rheumatoid arthritis, rheumatic fever, and mild infection. Large doses cause acid-base imbalance and respiratory disturbances and can be fatal, especially in children. Acetaminophen (known by trade name Tylenol), which does not cause gastric irritation but does lower fever and relieve pain, is often substituted for Aspirin.

This drug is used today to lower fevers and reduce inflammation, especially those caused by rhumatic fever and arthritis.

Acetylsalicylic acid will thin the blood and therefore it will, in small doses prevent heart attack, stroke & unstable angina. Because of its ability to thin the blood Acetylsalicylic Acid will inhibit the formation of blood clots.

It`s most common use is to relieve headaches as well as muscle & joint pain. Acetylsalicylic Acid interferes with the bodys synthesis of specific POSTAGLANDINS. These compounds are produced by almost every tissue in the body and control the substances involved in the transmission of nerve impulses which participate in the body`s defences against infection. Postaglandins have been shown to bring on fever and play a major role in inflammation.

Acetylsalicylic acid also has an antiplatelet effect by inhibiting the production of thromboxane, which under normal circumstances binds platelet molecules together to create a patch over damaged walls of blood vessels. Because the platelet patch can become too large and also block blood flow, locally and downstream, aspirin is also used long-term, at low doses, to help prevent heart attacks, strokes, and blood clot formation in people at high risk of developing blood clots. It has also been established that low doses of aspirin may be given immediately after a heart attack to reduce the risk of another heart attack or of the death of cardiac tissue. Aspirin may be effective at preventing certain types of cancer, particularly colorectal cancer.

The main undesirable side effects of aspirin taken by mouth are gastrointestinal ulcers, stomach bleeding, and tinnitus, especially in higher doses. In children and adolescents, aspirin is no longer indicated to control flu-like symptoms or the symptoms of chickenpox or other viral illnesses, because of the risk of Reye's syndrome.

Acetylsalicylic acid is part of a group of medications called nonsteroidal anti-inflammatory drugs (NSAIDs), but differs from most other NSAIDs in the mechanism of action. Though it, and others in its group called the salicylates, have similar effects (antipyretic, anti-inflammatory, analgesic) to the other NSAIDs and inhibit the same enzyme cyclooxygenase, aspirin (but not the other salicylates) does so in an irreversible manner and, unlike others, affects more the COX-1 variant than the COX-2 variant of the enzyme.

At present other uses of this drug are under investigation such as there usefulness in prevention of certain cancers and dangerously high blood pressure which sometimes can occur in pregnancy. It`s effectiveness in the relief of migranes is currently being looked into.

Frankie is the freelance writer for e-commerce website in the chemistry. Guidechem.com is just a place for you to look for some chemicals. Our guidechem provide the most convenient conditions for the international buyers and let these leads benefit all the business people. Guidechem chemical B2B network provides information on china and global chemical market quotation and relative chemical Information. Guidechem Chemical Network providing the most complete information of the chemical industry.