2014年3月2日星期日

Providing high quality Palladium,dichlorobis(triphenylphosphine)

Palladium,dichlorobis(triphenylphosphine) is a kind of yellow crystals with Molecular Formula: C36H30Cl2P2Pd and Molecular Weight: 701.91. It is a coordination compound of palladium containing two triphenylphosphine and two chloride ligands. It is often used for palladium-catalyzed coupling reactions, prepared by reacting palladium(II) chloride with triphenylphosphine.

Palladium,dichlorobis(triphenylphosphine) is insoluble in water with the other properties: Density:g/cm3; Boiling Point:360 C at 760 mmHg; Melting Point:260C; Flash Point:181.7 C; CAS Registry Number:13965-03-2. Palladium,dichlorobis(triphenylphosphine) is stable at room temperature in closed containers under normal storage and handling conditions.When you store it, you should minder these: Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Store protected from moisture.

If you need buy some Palladium,dichlorobis(triphenylphosphine), this article will be very useful for you. These supply information all refer to Guidechem. Guidechem chemical B2B network provides information on china and global chemical market quotation and relative chemical Information.Guidechem Chemical Network providing the most complete information of the chemical industry.

1.Capot Chemical Co., Ltd.
Updatetime:Feb 27 2014
Purity:98% Min. Order:1/Kilogram Supply Ability:up to kgs Month/Kilogram
DetailDesc:701.90,C36H30Cl2P2Pd
Tel:86-571-85586718
Address:Joinhands Science Park, No.4028,Nanhuan Road

2.AOPHARM
Updatetime:Feb 27 2014
Purity:99%
DetailDesc:yellow solid
Tel:86-311-66600578
Address:C-2103 Wonder Business Square, 15 Yuhua West Rd.

3.Hangzhou Dayangchem Co., Ltd.
Updatetime:Feb 27 2014
DetailDesc:Dichloro-bis-(triphenylphosphine) palladium(II)
Tel:86-571-88938639
Address:B/2601 Fuli Building, 328# WenEr Rd. Hangzhou City 310012 China

4.Atomax Chemicals Co.,Ltd
Updatetime:Feb 26 2014
Purity:95%min Min. Order:mg/g/Gram Supply Ability:g/kg Month/Kilogram
DetailDesc:We are a leading global supplier and manufacturer of chiral chemicals, amino acids, aromatic and pyridine halogens, natural extracts and pharmaceutical raw materials. Those chemicals are widely used in the pharmaceutical and fine chemical industries and in research laboratories.
Tel:86-755-33239182
Address:Huiji302 Hutingju Sanwei Xixiang SHENZHEN 518126, China

5.run-biotech Co., Ltd.
Updatetime:Feb 24 2014
DetailDesc:Bis(triphenylphosphine)palladium(II) dichloride
Tel:86-21-61900721
Address:Room 3-201, No.787, Kangqiao Road, Pudong New District, Shanghai, China

6.Hui Chem Company Limited
Updatetime:Feb 27 2014
Purity:98% Min. Order:1/Gram Supply Ability:10 Month/Kilogram
DetailDesc:We could receive custom synthesis according to your requirements from lab scale to commercial scale
Tel:86-21-60542966
Address:Lane 299 Bisheng Rd,Pudong District

7.Nanjing Chemlin Chemical Co., Ltd.
Palladium,dichlorobis(triphenylphosphine)(CAS NO:13965-03-2)
Updatetime:Jan 24 2014
Purity:97.00%
DetailDesc:intermediates, drug discovery
Tel:86-25-83697070
Address:Rm.902 Longyin Plaza, No. 217 Zhongshan Rd.(N) Nanjing 210009,China

8.Rosewell Industry Co., Ltd
Palladium,dichlorobis(triphenylphosphine)
Updatetime:Jan 09 2014
DetailDesc: We are the leading supplier of APIs,inhibitors, animo-acids,peptide, other pharmaceutical intermediates, and custom synthesis products.
Tel:86-519-86202821
Address:Qixing building, Mingxin road, Changzhou,Jiangsu,China

9.Angene International Limited
Palladium,dichlorobis(triphenylphosphine)
Updatetime:Jan 08 2014
DetailDesc:You can find Bis(triphenylphosphine)palladium(II) chloride with most competitive price and high quality here. Welcome to inquire for stock confirming.
Tel:852-852-81916999
Address:4/F Silvercord Center Tower 1, 30 Canton Rd,KL,Hong Kong

Guidechem provide the most convenient conditions for the international buyers and let these leads benefit all the business people. If you need Palladium,dichlorobis(triphenylphosphine) or any other chemicals you can access to our Guidechem.

2014年2月27日星期四

Dess-Martin periodinane is used in many fields

Dess-Martin Periodinane, a hypervalent iodine compound, offers selective and very mild oxidation of alcohols to aldehydes or ketones. The oxidation is performed in dichloromethane or chloroform at room temperature, and is usually complete within 0.5 - 2 hours. It has the Synonyms: 1,2-Benziodoxol-3(1H)-one, 1,1,1-tris(acetyloxy)-1,1-dihydro-, and it is mostly known as DMP. It is a kind of white crystalline powder with Molecular Formula: C13H13IO8 and Molecular Weight: 424.14, the CAS Registry Number is 87413-09-0.

Dess-Martin periodinane is commercially available and decomposes only slowly. But Dess-Martin periodinane is heat and shock-sensitive, and shows an exotherm when heated >130 C. 2-Iodoxybenzoic acid (IBX), the impact-sensitive intermediate in the synthesis of the Dess-Martin periodinane, is available in a DMSO solution and is also used as an oxidizing agent.

Partial hydrolysis of Dess-Martin periodinane or incomplete acetylation gives a more effective oxidant, explaining why impure samples of this compound in many cases provide better results than the pure reagent. When reliable and convenient rate enhancement is desired, pure Dess-Martin periodinane may be decomposed with an equivalent of water immediately before or during its use.

Dess-Martin periodinane is mainly used as an oxidant for complex, sensitive and multifunctional alcohols. One of the reasons for its effectiveness is its high selectivity towards complexation of the hydroxylic group, which allows alcohols to rapidly perform ligand exchange; the first step in the oxidation reaction.

Proton NMR has indicated that using one equivalent of alcohol forms the intermediate diacetoxyalkoxyperiodinane. The acetate then acts as a base to deprotonate the α-H from the alcohol to afford the carbonyl compound, iodinane, and acetic acid.When a diol or more than one equivalent of alcohol is used, acetoxydialkoxyperiodinane is formed instead. Due to the labile nature of this particular periodinane, oxidation occurs much faster.

Using the standard Dess-Martin periodinane conditions, alcohols can be oxidized to aldehydes/ketones without affecting furan rings, sulfides, vinyl ethers, and secondary amides. Allylic alcohols are easily oxidized using this chemical, which are typically difficult to convert to their respective carbonyls using the typical oxidants.

Difluoro and monofluoro alcohols are more difficult to oxidize. Swern oxidation has been used, but a large excess of the oxidant had to be employed, and in some cases did not give reproducible results. Linderman and Graves found Dess-Martin periodinane(CAS NO: 87413-09-0) was partially successful, but side reactions occurred. Using the modified DM oxidant shown below, produced the wanted carbonyl in high yields. The reason Linderman and Graves chose tert-butyl alcohol as a ligand instead of acetate was due to its bulk and nonoxidizable characteristics. This was to minimize the unwanted byproduct acetic acid formed.

Learning more information about Dess-Martin periodinane, please access to guidechem. Guidechem Chemical Network providing the most complete information of the chemical industry.

2014年2月26日星期三

The main usages of Tetrabromobisphenol A

Tetrabromobisphenol A has the largest market among brominated flame retardants. It is a white to off-white powder melting point of 180-184 C; soluble in methanol and ether. It is produced by the bromination of bisphenol A with various solvents such as halocarbon alone, hydrobromic acid, aqueous alkyl monoethers, acetic acid or methanol. 

Tetrabromobisphenol A(CAS NO:79-94-7) is a derivative of bisphenol A and is synthesized from this substance. Most commercial Tetrabromobisphenol A products are of a relatively low purity, in fact containing a mixture of products brominated to varying extents. This is not generally considered to be a drawback, since in most applications of this substance (i.e. flame-retarding) it is the average %Br that is of importance. The mixture resulting from the bromination of bisphenol A is therefore not purified, allowing a more efficient, lower cost product.

Tetrabromobisphenol A can be used as reactive and additive flame retardant. In the reactive application, it is bound chemically to the polymers. The main use are epoxy resins of printed circuit boards. As an additive flame retardant it is used in acrylonitrile butadiene styrene.

Tetrabromobisphenol A is used as a reactive flame retardant in epoxy, vinyl esters and polycarbonate resins. The main application of Tetrabromobisphenol A in epoxy resins is in PCB where the bromine content may be 20% by weight. It is used also as a flame retardant in polymers such as ABS, polystyrenes, phenolic resins, adhesives, paper, and textiles and others. It can be combined with a synergist such as antimony trioxide for maximum flame retardant performance. Tetrabromobisphenol A may also be used as a parent compound for the production of other commercial flame retardants.

Tetrabromobisphenol A is the largest volume brominated flame retardant in production today to improve fire safety of mainly electrical and electronic equipment. The main application of this chemical is as a reactive flame retardant in laminates for an estimated 90+% of printed wiring boards. It is also used as an additive flame retardant in ABS plastics. It is chemically bound in these applications and has no potential for emissions to the environment Among all the different flame retardants that can be used in printed wiring boards, Tetrabromobisphenol A is the most well researched flame retardant.

According to both the WHO and the currently undertaken EU Risk Assessments, Tetrabromobisphenol A(CAS NO:79-94-7) has little potential for bioaccumulation and presents no significant health effects of concern. Also, No emissions from circuit boards could be detected Tetrabromobisphenol A is currently being risk-assessed at the EU-level.

Learning more information about Tetrabromobisphenol A, please access to guidechem.Guidechem Chemical Network providing the most complete information of the chemical industry.

2014年2月25日星期二

MSDS information of N,N-Dimethylethanolamine

Basic properties of N,N-Dimethylethanolamine

Molecular Formula: C4H11NO
Synonyms: 2-(Dimethylamino)ethanol; Deanol; 2-Dimethylamine Ethanol;
Appearance: clear to pale yellow liquid
Molecular Weight:89.14
Density:0.888; Boiling Point:139 C; Melting Point:-70 C; Flash Point: 40 C
Storage Temperature: Flammables area
Solubility: miscible in water
Stability:Stable. Flammable. Incompatible with oxidizing agents, copper, copper alloys, zinc, acids, galvanised iron. Hygroscopic.
EINECS: 203-542-8
CAS Registry Number: 108-01-0
Usage:Medication, catalyst

Potential Health Effects

Eye:Contact N,N-Dimethylethanolamine with eyes may cause severe irritation, and possible eye burns. Lachrymator (substance which increases the flow of tears). 
Skin: it may cause severe irritation and possible burns, may be harmful if absorbed through the skin. 
Ingestion: if ingest it , may cause burns to the digestive tract, may be harmful if swallowed. 
Inhalation: N,N-Dimethylethanolamine may cause severe irritation of the respiratory tract with sore throat, coughing, shortness of breath and delayed lung edema. 
Chronic: Possible risk of harm to the unborn child. 

First Aid Measures

Eyes:Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately. Do NOT allow victim to rub eyes or keep eyes closed. Extensive irrigation with water is required (at least 30 minutes). 
Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Destroy contaminated shoes. 
Ingestion: Never give anything by mouth to an unconscious person. Get medical aid immediately. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water. 
Inhalation:Get medical aid immediately. Remove from exposure and move to fresh airimmediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. 

Fire Fighting Measures

As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Vapors may form an explosive mixture with air. Vapors can travel to a source of ignition and flash back. Containers may explode in the heat of a fire. Flammable liquid and vapor. Vapors may be heavier than air. They can spread along the ground and collect in low or confined areas. 

In case of fire, use water, dry chemical, chemical foam, or alcohol-resistant foam. Do NOT get water inside containers. For large fires, use water spray, fog or alcohol-resistant foam. Cool containers with flooding quantities of water until well after fire is out. 

Handling and Storage 

Wash thoroughly after handlingN,N-Dimethylethanolamine (CAS NO:108-01-0) .Remove contaminated clothing and wash before reuse. Ground and bond containers when transferring material. Do not get in eyes, on skin, or on clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Do not ingest or inhale. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames. Use only with adequate ventilation. Keep N,N-Dimethylethanolamineaway from heat, sparks and flame.

Store N,N-Dimethylethanolamine in a tightly closed container. Store it in a cool, dry, well-ventilated area away from incompatible substances. Flammables-area. Store protected from light. 

Learning more information about N,N-Dimethylethanolamine, please access to guidechem. Guidechem Chemical Network providing the most complete information of the chemical industry.

2014年2月24日星期一

Solve your questions about Mebendazole

Mebendazole is a highly effective, broad-spectrum antihelmintic indicated for the treatment of nematode infestations, including roundworm, whipworm, threadworm, and hookworm. It is poorly absorbed and has no systemic effects. Here I have some questions and answers about this medicine, it may solve your problems.

I have threadworms and took 1 tablet of Mebendazole 4 days ago but still I poop them out?

Mebendazole (CAS NO:31431-39-7) kills the worms, but not their eggs which can survive for two weeks. Therefore, you also need strict hygiene measures for two weeks after taking medication to prevent you from swallowing eggs which may cause a new infection. 

You may see dead ones for up to 2 weeks but that is if you dont get RE-infected. If you do then you need another round of meds. These worms eggs can live outside the body for up to 2 weeks also so make sure you wash all your bed clothes and under cloths and wash your hands very well when you are done. Actually just take a shower after you have decontaminated your living area.

Does Mebendazole kill the good intestinal bacteria, or only the worms?

Only the worms. Mebendazole inhibits microtubule formation and glucose uptake in helmiths. Its a spindle poison that inhibits chromosome nondisjunction-in English, it keeps DNA from replicating. It can cause harm to you (more than the normal gut flora), causing low blood cell counts, rashes, and it can cause your liver enzymes to elevate. A well known side effect is diarrhea, nausea and vomiting. Sometimes the cure is worse than the problem.

Would a one time Mebendazole pill kill my tapeworm?

I'm aware of mebendazole being used to treat tapeworm infection. It's normally used for other helminth, yes, but not tapeworm. This is an unlabeled use. That means it's not one suggested by the manufacturer but that doesn't mean it won't work. A lot of drugs have unlabeled uses. Like low doses of aspirin used to help prevent blood clots when it was found to interfere with platelet aggregation. 

And how atropine sulfate, for dilating and paralyzing the pupil for eye examination, mebendazole(CAS NO:31431-39-7) is also used to reduce oral secretions when the ophthalmic drops are used under the tongue. Mebendazole was originally developed for other uses but these "side effects" were found to be useful as well. Megace was developed to relieve the symptoms of certain cancers and of AIDS as well as the effects of the treatments for these diseases and the side effect of increased appetite proved to be most beneficial as these conditions typically suppress the appetite and result in weight loss. 


Learning more information about mebendazole, please access to guidechem.Guidechem Chemical Network providing the most complete information of the chemical industry.

2014年2月23日星期日

Hot supply Fluorescent Brightener KSN

Chemical and physical properties

Synonyms:Brightener 184; KeyfluorWhite PL; NSC 158163; O-B TECH; OB; TBO; Tinopal OB;
Molecular Formula:C26H26N2O2S     Molecular Weight:430.562
Appearance:Bright Yellow powder
Boiling Point:531.2 C at 760 mmHg; Melting Point:196-202 C; Flash Point:275.1 C
Stability:Stable. Incompatible with strong oxidizing agents.
EINECS:230-426-4    CAS Registry Number:7128-64-5

Usages and storage

Fluorescent Brightener KSN is mainly be used in whitening of polyester, polyamide, polyacrylonitrile fiber, the plastic film and all plastic pressing process. It can suitable for synthesizing high polymer including polymeric process. When we store it :Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

Where find Fluorescent Brightener KSN

Guidechem is just a place for you to look for some chemicals. Guidechem provide the most convenient conditions for the international buyers and let these leads benefit all the business people. Now I will list some suppliers of Fluorescent Brightener KSN in guidechem for you.

AFINE CHEMICALS LIMITED
Updatetime:Feb 21 2014
Min. Order:1/Gram Supply Ability:10 Month/Metric Ton
DetailDesc:OPTICAL BRIGHTENER OB
Tel:86-571-85232161
Address:6th Floor, Block C, 7th Building, Xigang Xinjie, Xihu Industrial Park, Sandun Town, Hangzhou, China

HUTONG GLOBAL CO.,LTD
Updatetime:Feb 21 2014
DetailDesc: CAS Number: 7128-64-5 Molecular formula: C26H26SO2N2 Technical conditions: Appearance: Bright yellow crystal powder Melting point: 198-201centigrade Content: ≥99.0% Use: It is used in thermoplastic plastics. PVC, PE, PP, PS, ABS, SAN, SB, CA, PA, PMMA, acrylic resin.
Tel:86-22-59853797
Address:chagugang,wuqing district,Tianjin,China

Hangzhou Dayangchem Co., Ltd.
Fluorescent Brightener KSN
Updatetime:Feb 21 2014
DetailDesc:2,5-bis-(5-tert-Butyl-2-benzoxazolyl)thiophene
Tel:86-571-88938639
Address:B/2601 Fuli Building, 328# WenEr Rd. Hangzhou City 310012 China

Shanghai Dell Chemical Co.Ltd
Fluorescent Brightener KSN
Updatetime:Feb 19 2014
Purity:NLT99% Min. Order:1/Kilogram Supply Ability:100 Year/Metric Ton
DetailDesc:Shanghai Dell Chemical Co.Ltd. is specialized in trading and developing active pharmaceutical ingredients, intermediates, API, and custom synthesis according to client’s requirements.
Tel:86-21-51950635
Address:Nianjiabang Rd, Pudong, Shanghai

run-biotech Co., Ltd.
Fluorescent Brightener KSN
Updatetime:Feb 08 2014
DetailDesc:2,5-bis(5-tert-butyl-2-benzoxazolyl)thiophene
Tel:86-21-61900721
Address:Room 3-201, No.787, Kangqiao Road, Pudong New District, Shanghai, China

Jinan Haohua Industry Co., Ltd.
Fluorescent Brightener KSN(CAS NO:7128-64-5)
Updatetime:Feb 21 2014
Purity:99 Min. Order:1/Kilogram Supply Ability:100 Year/Metric Ton
Tel:0086-531-58773055
Address:No.59 Gongye South RD

HEBEI CUI FENG IMPORT&EXPORT TRADE CO.,LTD
Fluorescent Brightener KSN
Updatetime:Feb 21 2014
Supply Ability:Success 
DetailDesc:2,5-bis-(5-tert-Butyl-2-benzoxazolyl)thiophene
Tel:86-311-80955068
Address:No 98 Gongnong Street,Shijiazhuang Hebei,China

Guidechem provide the most convenient conditions for the international buyers and let these leads benefit all the business people. If you need Fluorescent Brightener KSN or any other chemicals you can access to our Guidechem.

2014年2月21日星期五

Different studies on Bromacil lithium salt

Bromacil lithium salt is a light tan solid at room temperature. It has a mass of 267 D. It is not routinely produced as a solid. Rather, for commercial use it is prepared by dissolving bromacil in a solution of lithium hydroxide(LiOH). A laboratory preparation of bromacil lithium salt for regulatory study purposes used a ratio of 6 moles LiOH to one mole bromacil in methanol solvent. 

OEHHA does not have information on the molar ratio or solvent used for commercial purposes. Commercial preparations supplied for regulatory testing purposes were reported to be an amber liquid which contained 21-22% bromacil lithium salt.

Bromacil lithium salt (CAS NO. :7726-95-6) is an herbicide which inhibits photosynthesis. It is used for weed control on rights-of-way. In California, 4,478 lbs were applied in the year 2000. Bromacil lithium salt is produced for commercial use by dissolving bromacil in a solution of lithium hydroxide. It is a weak organic acid, with limited solubility. Much greater solubility is achieved in the ionic form produced by reaction with lithium hydroxide. 

Developmental studies with Bromacil lithium salt in experimental animals have found adverse effects including death of the embryo, fetus, or pup, malformations, and retarded development. While several studies have not found similar effects, multiple differences in study design make comparisons difficult. Developmental studies in rats by gavage found roughly similar molar levels of bromacil and lithium required to produce adverse developmental effects.

A small study with Bromacil lithium salt in humans found no association with alterations of the menstrual cycle or reproductive hormones in healthy females treated at therapeutic doses of Bromacil lithium salt. Two small studies found no association of female sexual dysfunction with Bromacil lithium salt treatment. Some studies in mice and rats treated with this compound have found reduced female reproductive capacity. 

However, several other studies have not found such effects. Multiple differences in study design make comparisons difficult. Adverse changes in parenting behavior have been observed in rats treated with lithium orally or by injection, and pup death or developmental delay has been reported after lactational exposure to lithium. 

Reproductive studies with Bromacil lithium salt(CAS NO. :7726-95-6) in rats and mice, and chronic studies in rats and dogs have found no adverse male reproductive effects. A chronic study in mice found increased testicular atrophy among mice treated with high doses of bromacil in diet for 12-18 months. Testis weights in bromacil-treated mice that survived to terminal necropsy were not affected.

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