Diethylamine used in medicine

Diethylamine is a secondary amine with the molecular structure CH3CH2NHCH2CH3 (also written as C4H11N). It is a flammable, strongly alkaline liquid. It is miscible with water and ethanol. It is a colorless liquid which often appears brown due to impurities. It is volatile and has a strong unpleasant odor.

Diethylamine is manufactured from ethanol and ammonia and is obtained together with ethylamine and triethylamine. It is used as a corrosion inhibitor and in the production of rubber, resins, dyes and pharmaceuticals. Diethylamine is a corrosive chemical and contact with skin may cause irritation or burns.

Physical properties:

Molecular weight: 73.14
Boiling point: 55.5°C (760 mm Hg)
Color: colorless liquid
Specific gravity: 0.71 (water = 1)
Formula: (C2H5)2NH
Vapor pressure at 20°C: 195 mm Hg
Flash point (closed cup): less than -18°C
Odor: fish, ammonia-like
Synonyms: diethamine; N-ethyle-ethanamine
CAS NO.: 109-89-7 

Diethylamine vapor is a severe irritant to mucous membranes, eyes, and skin. Rabbits repeatedly exposed to 50 ppm for 7 hours daily showed corneal damage and pulmonary irritation. In one reported human case, liquid splashed into the eye caused immediate intense pain. In spite of emergency irrigation and treatment, the cornea became swollen and cloudy. Some permanent visual impairment resulted. Contact with the liquid causes vesiculation (blisters) and necrosis (death of tissue) of the skin.

Diethylamine is used in preparation of textile finishing agents, surfactants, rubber processing chemicals, agricultural chemicals, and pharmaceuticals. It is also used as a corrosion inhibitor in iron, steel, and metal industries. 

Sometimes, it may be used as a polymerization inhibitor and catalyst in the polymer industry and as an intermediate in the dye industry. The other usages of Diethylamine is used as a depilatory of animal skins and in electroplating solutions.

In medicine, Diethylamine salicylate is widely used, it is used to treat muscular aches, sprains, and strains. It contains a mixture of ingredients that have a warming and pain-relieving effect that can help treat these types of conditions.

Diethylamine is available as a cream that is rubbed into the skin.You should try this medicine on a small area of skin first to make sure that you do not have a bad reaction to it.This cream should be applied sparingly. If you have sensitive skin or if you apply this medicine in hot weather or after a hot bath you may experience some discomfort.Speak to your doctor if your symptoms do not improve or if they get worse during treatment with Diethylamine.


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