2013年11月25日星期一

Some Serious side effects of Citalopram Hydrobromide you should pay attention to

Citalopram is an antidepressant drug of the selective serotonin reuptake inhibitor (SSRI) class. It has U.S. Food and Drug Administration (FDA) approval to treat major depression, which it received in 1998 and is prescribed off-label for other conditions. In UK, Germany, Portugal, Poland, and most European countries it is licenced for depressive episodes and panic disorder with or without agoraphobia. In Spain it is also used for obsessive-compulsive disorder.

Citalopram hydrobromide(CAS NO:59729-32-7) is a depression medication that is used to treat major depression and severe mood swings. It is used for treating most depression cases, except for bipolar depression, as it may actually aggravate the symptoms, or cause sudden unprecedented and rapid mood swings from depressive moods to manic moods. 

The mechanism of action of citalopram hydrobromide(CAS NO:59729-32-7) is similar to those of other anti-depression drugs. It acts on the brain and boosts the serotonin levels in the brain. Serotonin is one of the chemical messengers of the central nervous system, which is known to elevate the mood of a person. However, just as there are two sides of every coin, there are certain citalopram hydrobromide serious side effects that people taking this medication must be aware of.

There is another class of anti-depressant drug which is known as MAO (monoamine oxidase) inhibitors. Citalopram hydrobromide is known to have drug interactions with this class of drugs. These drug interactions can often prove to be fatal, hence, it is extremely important to give a proper and detailed history of the drugs and medications that you are taking. If you are on MAO inhibitors, then you should stop taking these drugs at least two weeks prior to taking citalopram hydrobromide.

One of the side effects is the development of an allergic reaction to citalopram hydrobromide. There are certain people who have an idiosyncratic allergy to this drug. In such cases, normally after a single dose itself, the person starts developing an allergic reaction to it, like rashes, itching, fever, irritability, excessive sweating etc. Thus, one should be aware of this possibility, and if he or she recognizes such signs of an allergic reaction, then he/she should stop the intake of the drug and bring the attention of the doctor to this anaphylactic reaction immediately.

Another most dangerous side effect is the possibility of citalopram hydrobromide causing suicidal thinking and suicidal tendencies if taken on a long term basis. This may especially occur if the person develops another parallel depressive disorder. This is one of the reasons why this drug is not given to anyone below 18 years of age.

In certain cases, there may be worsening of symptoms seen, like increased frequency of mood swings, going into extreme depression, suicidal tendencies etc.

For women that are pregnant or are breastfeeding, the safety of this drug is still questionable, as some studies have shown that citalopram hydrobromide maybe responsible for birth defects, although these findings are yet to be validated. Hence, it is best to avoid this drug during pregnancy or while breastfeeding.

Never overcompensate for a missed drug dose by taking a double dose while on citalopram hydrobromide, as an overdose of this drug can have dire consequences. Hence, it is best to simply take a dose as soon as one remembers. Also, do not abruptly stop the intake of citalopram hydrobromide, because it may lead to withdrawal symptoms.

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