2013年12月11日星期三

Side effects of Sitagliptin phosphate monohydrate

Sitagliptin phosphate monohydrate is an oral diabetes medicine that helps control blood sugar levels; It works by regulating the levels of insulin your body produces after eating. It is for people with type 2 diabetes (non-insulin-dependent) diabetes.

It is sometimes used in combination with other diabetes medications, but is not for treating type 1 diabetes.Sitagliptin phosphate monohydratemay (cas no:654671-77-9)also be used for purposes not listed in this medication guide.

In this article, we will talk about the side effects of Sitagliptin phosphate monohydrate from Consumer and Healthcare Professionals aspects. Firstly, let’s learning the side effects for Healthcare Professionals.

For Healthcare Professionals

1.Gastrointestinal: Gastrointestinal side effects have included abdominal pain, nausea, and diarrhea. Postmarketing experience has included constipation, vomiting, acute pancreatitis, including fatal and nonfatal hemorrhagic and necrotizing pancreatitis.
2.Respiratory: Respiratory side effects have included nasopharyngitis and upper respiratory tract infection.
3.Nervous system: Nervous system side effects have included headache.
4.Metabolic: Metabolic side effects have included hypoglycemia.
5.Hepatic: Hepatic side effects have included postmarketing reports of hepatic enzyme elevations.
6.Renal: Renal side effects have included postmarketing reports of worsening renal function, including acute renal failure, sometimes requiring dialysis.
7.Hypersensitivity: Hypersensitivity side effects have included anaphylaxis, angioedema, and exfoliative skin conditions including Stevens-Johnson syndrome. Postmarketing hypersensitivity reactions have included rash, urticaria, and cutaneous vasculitis.
8.Musculoskeletal: Arthralgia, myalgia, pain in extremities, and back pain have been reported postmarketing.

Then the side effects for Consumers

1.Common side effects of Sitagliptin phosphate monohydrate are: hives, difficulty breathing, swelling of your face, lips, tongue, or throat.Get emergency medical help if you have any of these signs of an allergic reaction.

2.The common serious side effects of Sitagliptin phosphate monohydrate are: pancreatitis - severe pain in your upper stomach spreading to your back, nausea and vomiting, loss of appetite, fast heart rate; or fever, sore throat, and headache with a severe blistering, peeling, and red skin rash.Stop taking sitagliptin and call your doctor at once if you have a serious side effect

3.Less serious side effects may include: runny or stuffy nose, sore throat; headache; or nausea, stomach pain, diarrhea.

This is not a complete list of side effects about Sitagliptin phosphate monohydrate and others may occur. Call your doctor for medical advice about side effects. 

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