Acetoacetanilide for the environment and hunman health

Acetoacetanilide is a chemical intermediate used in the production of pigments. It is a kind of white to off-white powder, with Molecular Formula:C10H11NO2 and Molecular Weight:177.2. It is stable, combustible,incompatible with strong oxidizing agents. Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. The CAS Registry Number is 102-01-2.

Acetoacetanilide is used as intermediate for the manufacture of organic pigments and dyestuffs. It is then isolated and transported under closed conditions to pigment manufacturing facilities. There is no known direct or consumer use. Non-aqueouswastes from manufacture are incinerated, and aqueous wastes are sent to a wastewater treatment facility for treatment.

For the environment, Acetoacetanilide(CAS NO: 102-01-2) is of low concern to aquatic organisms and is considered inherently biodegradable. The predicted environmental concentration is lower than the predicted no effect concentration. It is therefore currently considered of low potential risk and low priority for further work.

It is a solid with a low vapor pressure therefore; substantial airborne concentrations are not likely.  Solubility studies indicate that it in the environment will partition into water, where biodegradation then occurs. Data from environmental toxicity studies indicate that Acetacetanilide is of low concern for aquatic or plant species. 

Emissions to the terrestrial environment are not considered, as there is no direct release to soil and no emission to air. Based on the results from the use emission scenarios it can be concluded that Acetoacetanilide will not cause any harmful effects on the environment during the whole life cycle. With regards to the proposed emission scenarios, it is of no immediate concern for the environment. 

For the hunman health, the intended uses of Acetoacetanilide are industrial only, and there are no downstream uses that would result in exposure of consumers. It is used as intermediate and the amount of residual starting material in the end products is negligible. 

Considering the work pattern in the uses of Acetoacetanilide and the non-relevance of indirect exposure it can be excluded that workers are exposed to Acetoacetanilide from more than one emission source. According to the Exposure Scenarios, Acetoacetanilide does not pose an unacceptable risk to human health. Overall the substance is of no immediate concern for man when used within the boundaries of the operational controls and risk management measures described for its uses.

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