2014年1月6日星期一

Give you the summary of Thiophene-2-ethylamine

Basic information:

IUPAC Name: 2-thiophen-2-ylethanamine  
Empirical Formula: C6H9NS 
Molecular Weight: 127.2074 
Index of Refraction: 1.567 
Molar Refractivity: 37.72 cm3 
Molar Volume: 115.4 cm3
Surface Tension: 43.3 dyne/cm 
Density: 1.102 g/cm3 
Flash Point: 74.6  C 
Enthalpy of Vaporization: 43.59 kJ/mol 
Boiling Point: 199.7 C at 760 mmHg 
Vapour Pressure: 0.337 mmHg at 25C 
Storage temp: Refrigerator (+4 C) 
Sensitive: Air Sensitive 
Appearance: colorless to yellow liquid
EINECS:250-196-9
CAS Registry Number:30433-91-1

Usages of Thiophene-2-ethylamine:

Thiophene-2-ethylamine is lipid-lowering drugs, platelet aggregation inhibitors, cardiovascular vasodilators, 5-lipoxygenase inhibitors and a variety of antimicrobial drugs and other biologically active drug intermediates, mainly used for the synthesis of cardiovascular and cerebrovascular disease drugs ticlopidine hydrochloride. As downstream drug development, this compound paid more attention to the fine chemical intermediates.

In commercial Thiophene-2-ethylamine(CAS NO:30433-91-1) can be prepared by the reaction of butane and sulfur. Thiophenes are also prepared by the reaction of diketones with Lawesson's reagent. This compoud and its derivatives exist in petroleum or coal. It is used as a solvent and chemical intermediate. Its derivatives are used in manufacturing dyes, aroma compounds and pharmaceuticals. Thiophene-2-ethylamine is used as an intermediate to manufacture pharmaceuticals such as antiplatelet drug (Clopidogrel, Ticlopidine) used to lessen the chance of heart attack or stroke.

MSDS of Thiophene-2-ethylamine

1.Potential Health Effects
Eye: Causes eye irritation. May cause chemical conjunctivitis. 
Skin: Causes skin irritation. May be harmful if absorbed through the skin. 
Ingestion: May cause irritation of the digestive tract. May be harmful if swallowed. 
Inhalation: Causes respiratory tract irritation. May be harmful if inhaled. Can produce delayed pulmonary edema. 
Chronic: No information found. 

2.First Aid Measures 
Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. 
Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. 
Ingestion: Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water. Wash mouth out with water. 
Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Do NOT use mouth-to-mouth resuscitation. 

Supply information in guidechem

1.AOPHARM
Thiophene-2-ethylamine
Updatetime:Jan 06 2014
Purity:99%
DetailDesc:Pale yellow clear liquid, long buy become red
Tel:86-311-66600578
Address:C-2103 Wonder Business Square, 15 Yuhua West Rd.

2.Capot Chemical Co., Ltd.
Thiophene-2-ethylamine
Updatetime:Dec 31 2013
Purity:98% Min. Order:1/Kilogram Supply Ability:up to kgs Month/Kilogram
DetailDesc:127.21,C6H9NS
Tel:86-571-85586718
Address:Joinhands Science Park, No.4028,Nanhuan Road

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