Astragaloside IV, the main component of the traditional Chinese medicine astragalus membra-naceus, has been shown to inhibit inflammation, oxidation, and apoptosis, and exerts immu-noregulatory effects.
Astragaloside IV is one of the main active compounds of Astragalus membranaceus Bunge. Experimental studies from several laboratories,have provided abundant evidence demonstrating the explicit cardiovascular-protective effects of Astragaloside IV(CAS NO:84687-43-4).
Now, let’s talk about what can we benefit from Astragaloside IV in detail.
1.Immunostimulant: acting through a number of different pathways, especially,by increasing the number of stem cells in the spinal cord and lymphatic tissue and encouraging them to develop into active immune cells or stimulating production of immunoglobulins and macrophages.
2.Neuroprotective: in traditional Chinese medicine, astragalus root extract is used to treat neurodegenerative diseases. One study demonstrated the capacity of astragaloside IV(CAS NO:84687-43-4) to protect dopaminergic neurons (progressive degeneration of dopaminergic neurons leads to the development of Parkinson's disease).
3.Antibacterial: as demonstrated by in vitro studies on Shigella dysenteriae, Streptococcus haemolyticus, Diplococcus pneumoniae and Staphylococcus aureus.
4.Antiviral: inhibiting replication of certain viruses such as coxsackie, responsible for myocarditis (inflammation of the heart muscle). In both animal and human studies, they were shown to stimulate endogenous interferon production and to maximise its effect on viral infections.
5.Anti-inflammatory: as shown in certain animal models. The ability of astragaloside IV to stem inflammation of the airways in chronic asthma has been reported in studies on mice.
6.Inhibitory: against formation of the AGEs involved in neuropathic complications of diabetes.
7.Protective: against the toxic effects of chemotherapy. Astragalus extract boosts resistance to the immunosuppressive effects of chemotherapy drugs by encouraging macrophages to product interleukin 6 and tumour necrosis factor.
8.Antioxidant: inhibiting lipid peroxidation by 40% in vitro. These antioxidant properties may go some way to explaining the cardio- and neuro-protective effects of astragalus and astragaloside IV.
9.Cardioprotective: with studies highlighting health benefits for patients with congestive cardiac insufficiency and angina pectoris. Astragalus extracts have a cardiotonic effect.
With so many beneficial properties, particularly immunostimulant, anti-inflammatory, antioxidant and anti-glycation, Astragaloside IV is a truly essential anti-aging supplement. Its exceptional properties are due to Astragaloside IV specific ability to activate telomerase, thus slowing down the shortening of telomeres, and extending cell lifespan. Shortening of telomers is associated with cellular ageing and the development of age-related diseases.
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