2013年8月7日星期三

Be careful to Oxalic acid dehydrate

1. Basic information of Oxalic acid dehydrate

MSDS Name: Oxalic acid dehydrate
Synonyms: Ethanedioic acid dihydrate.
Appearance: white powder.
CAS No 6153-56-6

2. Hazards Identification of Oxalic acid dehydrate
1Danger!
Oxalic acid dehydrate may cause burns by all exposure routes. Harmful if swallowed, inhaled, or absorbed through the skin. There are possible risks of harm to the unborn child. It may cause kidney damage.
2Potential Health Effects 
1)        Eye: Oxalic acid dehydrate causes eye burns. May result in corneal injury. Causes redness and pain. 
2)        Skin: Harmful if absorbed through the skin. Oxalic acid dehydrate causes severe skin irritation and possible burns. Rare chemical burns may occur from oxalic acid and may cause hypocalcemia. Gangrene has occurred in the hands of people working with oxalic acid solutions without rubber gloves. The skin lesions are characterized by cracking of the skin and the development of slow-healing ulcers. The skin may be bluish in color, and the nails brittle and yellow.
3)        Ingestion: Oxalic acid dehydrate causes gastrointestinal tract burns. Oxalic acid is toxic because of its acidic and chelating properties. It is especially toxic when ingested. As little as 5 grams (71 mg/kg) may be fatal. Ulcerations of the mouth, vomiting of blood, and rapid appearance of shock, convulsions, twitching, tetany, and cardiovascular collapse may occur following ingestion of oxalic acid or its soluble salts. Oxalic acid can bind calcium to form calcium oxalate which is insoluble at physiological pH. Calcium oxalate thus formed might precipitate in the kidney tubules and the brain. Hypocalcemia secondary to calcium oxalate formation might disturb the function of the heart and nerves. 
4)        Inhalation: Oxalic acid dehydrate causes chemical burns to the respiratory tract. Inhalation of oxalic acid dust or vapor produces irritation of the respiratory tract, protein in the urine, nosebleed, ulceration of the mucous membranes, headache, nervousness, cough, vomiting, emaciation, back pain (due to kidney injury), and weakness.  Chronic: Inhalation of oxalic acid dust or mist over a long period of time might result in weight loss and respiratory tract inflammation. Rats administered oxalic acid at 2.5 and 5% in the diet for 70 days developed depressed thyroid function and weight loss. A study of railroad car cleaners in Norway who were heavily exposed to oxalic acid solutions and vapors revealed a 53% prevalence of urolithiasis (the formation of urinary stones), compared to a rate of 12% among unexposed workers from the same company.

3. First Aid Measures
1)        Eyes: In case of contact, immediately flush eyes with plenty of water for a t least 15 minutes. Get medical aid immediately. 
2)        Skin: In case of contact, immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid immediately. Wash clothing before reuse.
3)        Ingestion: If swallowed, do NOT induce vomiting. Get medical aid immediately. If victim is fully conscious, give a cupful of water. Never give anything by mouth to an unconscious person. 
4)        Inhalation: If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.  Notes to Physician: Treat symptomatically and supportively. 
5)        Antidote: Intravenous administration of calcium gluconate or calcium chloride may be required if hypocalcaemia or hypocalcaemia tetany occur.


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