6-Hydroxynicotinic acid is an important chemical synthesis

6-Hydroxynicotinic acid with the CAS number of 5006-66-6, it can be called 1,6-dihydro-6-oxo-3-pyridinecarboxylicacid,2-Hydroxy-5-pyridinecarboxylicacid,2-hydroxypyridine-5-carboxylicacid,5-carboxy-2(1h)-pyridinone,6-hydroxy-3-pyridinecarboxylicacid,6-hydroxynicotinic acid. 6-Hydroxynicotinic acid is an off-white powder, it is used as building block in chemical synthesis. Here are the detail properties and safety profiles of 6-Hydroxynicotinic acid.

Chemical and physical properties

IUPAC Name: 6-oxo-1H-pyridine-3-carboxylic acid 
Empirical Formula: C6H5NO3
Molecular Weight: 139.1088
Polar Surface Area: 46.61 
Index of Refraction: 1.579
Molar Volume: 95.8 cm3
Molar Refractivity: 31.84 cm3
Surface Tension: 61 dyne/cm
Density: 1.451 g/cm3
Flash Point: 186 °C
Boiling Point: 384 °C at 760 mmHgH bond donors: 2
Melting point: >300 °C(lit.)
Vapour Pressure: 5.81E-07 mmHg at 25°C
H bond acceptors: 4
Freely Rotating Bonds: 1
Enthalpy of Vaporization: 69.45 kJ/mol
BRN: 472182
EINECS: 225-682-9
CAS NO.: 5006-66-6
Product Categories: We category 6-Hydroxynicotinic acid into Nitrogen cyclic compounds; blocks; Carboxes; Pyridines; Pyridine; Organic acids.

Safety profiles

Hazard Codes: Irritant Xi
Hazard Note: Irritant
TSCA: T
Risk Statements: 36/37/38
R36/37/38: 6-Hydroxynicotinic acid has Irritation to eyes, respiratory system and skin. 
Safety Statements: 26-36-24/25
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S36:Wear suitable protective clothing when deal with the accident of 6-Hydroxynicotinic acid. 
S24/25:Avoid 6-Hydroxynicotinic acid contact with skin and eyes. 
WGK Germany: 3


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