Hypericin(CAS NO: 548-04-9) is a kind of brown flowing powder, smells the unique fragrance, bitter taste, soluble in water. Hypericin may be blue-black or purple needle crystal. It is easily soluble in pyridine and other organic bases, a cherry red solution and was red fluorescence. The aqueous alkali solution of Hypericin is almost insoluble in other organic solvents. In pH11.5 less is red, pH11.5 above is green, and shows a red fluorescence. Melting point> 320 ℃ (decomposition).The main source of hypericin is extraction from the hypericum perforatum.
According to the 2000 report of the British Medical Journal study, comparing the efficacy of Hypericum perforatum with imipramine for the treatment of depression. The findings are both similar efficacy, but more acceptable to patients taking hypericin, which 26% of the patients occur adverse reactions after taking imipramine, give up taking the drug, as Hypericum perforatum group, only 3% of patients taking hypericin to give up. Hypericum perforatum (Melaleuca F) is that many people have studied herbs, clinical experience, drug generally safe.
By the Chinese Academy of Agricultural Sciences, Lanzhou Institute of Animal Husbandry and Veterinary submitted to the National Avian Influenza Reference Laboratory "the effect of hypericin to kill the H9N2 avian influenza virus and subtype H5N1 " test completed. The results showed that hypericin on highly pathogenic avian influenza virus killing effect is good, and finally kill rate is up to 100%.
Hypericin extract of Hypericum perforatum, has strong antiviral activity. For the control of avian influenza as a national new formulations are now available across the country to obtain a good response and effects; The clinical application of hypericin proved good results in prevention and treatment of influenza virus again. Because the long-term vaccine prevention and drug treatment, leading to influenza virus gradually mutate, was atypical of clinical symptoms, concurrent bladder inflammation, E. coli and other diseases, the proposed clinical use of drugs, with the appropriate medicine use, the effect is more precise.
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