Medicine name: Dexamethasone Sodium Phosphate for Injection

Specification: 5mg (by dexamethasone sodium phosphate meter)

Whether prescription drugs: prescription drugs

Main components: Dexamethasone sodium phosphate(CAS NO:2392-39-4 )

Indications

Dexamethasone Sodium Phosphate for Injection for the treatment of lymphoma, acute leukemia, ulcerative colitis, dermatitis, bronchial asthma, rheumatoid arthritis, rheumatoid arthritis, it also has a good effect on hematology, gastroenterology, dermatology, respiratory medicine, Division of Rheumatology class diseases.

Usage and dosage

General dose intravenous injection every 2-20mg; intravenous infusion should be diluted with 5% glucose injection. Dexamethasone sodium phosphate can be repeated dose 2-6 hours until a stable condition, but the high-dose administration is generally not more than 72 consecutive hours.

Dexamethasone Sodium Phosphate for Injection can also be used to relieve cerebral edema caused by malignant tumors, the first dose of intravenous injection of 10mg, followed by intramuscular injection every 6 hours 4mg, generally 12-24 hours patients can be improved gradually reduced for 2-4 days amount,5-7 days withdrawal. Inoperable brain tumor, the first dose of intravenous bolus injection 50mg, repeated after every two hours to give 8mg, every few days and then reduced to 2mg, 2-3 times given intravenously.

Dexamethasone Sodium Phosphate for intrathecal injection every 5mg, spaced 1-3 weeks for once injection; intra-articular injection usually every 0.8-4mg, according to the joint cavity size.

Pharmacological effects

Dexamethasone Sodium Phosphate for Injection is an kind of adrenal cortex hormones drugs. It has the functions of anti-inflammatory, anti-allergic, anti-rheumatic, immunosuppressive, the mechanisms of actions are in the following list:
anti-inflammatory effect: This product is to reduce and prevent tissue response to inflammation, thereby reducing the performance of inflammation. To inhibition of inflammatory cells, including macrophages and accumulation of leukocytes in inflammatory sites, and inhibition of phagocytosis, lysosomal enzyme release and synthesis of chemical mediators of inflammation and release.

Immunosuppression: Dexamethasone Sodium Phosphate can prevent or inhibit cell-mediated immune responses, delayed hypersensitivity reactions, reduction of T lymphocytes, monocytes, macrophages acid number of cells of the immune globulin and cell surface receptor binding capacity, and inhibition of interleukin synthesis and release, thereby reducing the T lymphocytes to lymphoblastoid cell transformation, and to alleviate the situation of the primary immune response extensions.

Dexamethasone Sodium Phosphate for Injection can also reduce immune review material through the basement membrane, and it can reduce the complement components and immunoglobulin concentrations.

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