Amoxicillin is not safe

Amoxicillin (INN), formerly amoxycillin (BAN), and abbreviated amox, is a moderate-spectrum, bacteriolytic, β-lactam antibiotic used to treat bacterial infections caused by susceptible microorganisms. It is usually the drug of choice within the class because it is better absorbed, following oral administration, than other β-lactam antibiotics. Amoxicillin is one of the most common antibiotics prescribed for children. The drug became available in 1972.

After amoxycillin became available, use rash comes. First let me tell you the symptoms of Amoxicillin rash.

The rash can appear as red or dark pink spots that are small and flat. Sometimes these spots will be raised or even hive-like in appearance. The rash can occur right after taking a dose or even up to two weeks after stopping the medication. An Amoxicillin rash generally starts on the abdomen and spreads to the chest, legs, arms and eventually the face. A non-allergic Amoxicillin rash does not itch, while the allergic version can itch and even blister. It is estimated that about 10% of children taking Amoxicillin will develop a rash.

The rash may be mild or severe and potentially life threatening. The following are all possible forms of Amoxicillin rashes.

1. Stevens-Johnson Syndrome

This is a very severe form of Amoxicillin allergic rash. The rash erupts into blisters and involves the mouth and mucous membranes. The top layer of skin then sheds and the patient is susceptible to skin infection as well. The person will feel flu-like and unwell. This condition can be life threatening and requires admission to the intensive care unit. Some consider these severe skin rashes similar to a major burn and are at an increased risk for disability and death.

2. Anaphylaxis

This is the most severe form of a rapidly progressing allergic reaction. Initial symptoms include hives and itching. As the condition progresses, the lips, tongue and airway begin to swell. The lungs tighten and bronchospasm causes wheezing and shortness of breath.As the condition progresses, the circulatory system collapses and death results without immediate life-saving emergency treatment.

3. Exfoliative Dermatitis

This is also a severe form of an Amoxicillin rash. The skin becomes red and begins to itch and scales may form. Then the skin sloughs off in large sheets. The person feels unwell, temperature regulation is difficult and a general sense of weakness develops. This condition often requires hospitalization.

4. Erythematous Rashes

Individuals sensitive to Amoxicillin or other penicillin type antibiotics can develop red appearing rashes. Commonly occurring symptoms include red raised bumps 1mm in size. Some can be flat while others are raised. Others may experience Erythema Multiforme in which red circles or target like lesions appear on the skin. These are generally larger than 1 cm in size and can appear anywhere on the body. Both types signify an allergic process.

5. Miscellaneous Rashes

Generalized exanthematous pustulosis results from an Amoxicillin allergy. Small pus filled blisters develop on various parts of the body. Hypersensitivity vasculitis causes inflammation of the blood vessels and appears as small non-raised red spots just below the surface of the skin.

6. Other Complications

A variety of other signs and symptoms can occur due to an Amoxicillin rash and include: nausea, GERD, diarrhea (watery or bloody), fever, chills, body ache, headache and a generalized sense of feeling unwell. Yeast infections often develop after antibiotic use and result in vaginal itching or thrush (oral candidiasis). Yeast is easily treated with antifungal creams or oral medication. Some report a hairy or black appearing tongue as a consequence of Amoxicillin use. Hives and progression to anaphylaxis is a feared complication of Amoxicillin allergy. Seizures rarely occur and demand immediate medical attention.

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