Basic knowledge of Aloe-emodin

1.Basic information:

Chemical Name :Aloe-emodin 
Appearance :Orange Powder 
Synonym:1,8-Dihydroxy-3-(hydroxymethyl)-9,10-anthracenedione;1,8-Dihydroxy-3-(hydroxymethyl)anthraquinone;3-Hydroxymethylchrysazin;3-Hydroxymethylchrysazine; Aloe-emodol; NSC 38628; Rhabarberone;
Category :Aromatics, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals
Molecular Formula :C15H10O5
Molecular Weight :270.24
CAS Number :481-72-1
Purity: 99.0%
Appearance :Orange Powder

Aloe-emodin is found in certain plants, including Aloe-emodin. It belongs to a family of compounds called anthraquinones, which have shown anti-inflammatory and anticancer effects. It shows significant inhibitory activity against the P-388 leukemia in mice when administered as a suspension in acetone-Tween 80. Has a specific in vitro and in vivo antineuroectodermal tumor activity. Cathartic.

2.Function and Usage: 

Aloe-emodin (AE), a hydroxyanthraquinone present in Aloe-emodin leaves, has a specific in vitro and in vivo antineuroectodermal tumor activity. The growth of human neuroectodermal tumors is inhibited in mice with severe combined immunodeficiency without any appreciable toxic effects on the animals. The compound does not inhibit the proliferation of normal fibroblasts nor that of hemopoietic progenitor cells. 

The cytotoxicity mechanism consists of the induction of apoptosis, whereas the selectivity against neuroectodermal tumor cells is founded on a specific energydependent pathway of drug incorporation. Taking into account its unique cytotoxicity profile and mode of action, AE might represent a conceptually new lead antitumor drug.

Aloe-emodin promotes the healing of minor burns and small wounds. Aloe-emodin juice or encapsulated powder result in reduced intestinal transit time. In heart disease patients, Aloe-emodin leaf, added to the diet, reduced total serum cholesterol, serum triglycerides, fasting and post prandial blood sugar levels 

3. Application: 

(1)Applied in food additives, Aloe-emodin is used as nutritious supplementary pharmaceutical.
(2)Applied in pharmaceutical field, it is used to treating constipation and expelling of toxin and treating .

(3)Applied in cosmetics field, it owns the effect of whitening, dispelling spot, anti-wrinkle, activating skin cells, making skin more te

4. Storage and shelf time: 

Storage: Store in cool and dry place, Keep away from strong light and heat. 
Packaging:1kg with double plastic container inside/Aluminum foil bag outside.                             

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