Oxandrolone, also known as oxandrin, is a drug first synthesized by Raphael Pappo while at Searle Laboratories, now Pfizer Inc., under the trademark Oxandrolone, and introduced into the United States in 1964. It is a synthetic anabolic steroid derivative of dihydrotestosterone with an oxygen atom replacing the 2 carbon and methylation in the 17 position.
Oxandrolone(CAS NO.: 53-39-4) was developed to treat conditions of muscle wasting and rapid weight loss, as is a common reason for inception with any anabolic steroid. Developed in 1964, by Searle Laboratories to treat such conditions, Searle is no longer in existence as it was bought and absorbed into Pfizer in 2003.
However, it was Searle’s development of Oxandrolone that is of importance because this is a pharmacy that has brought us some of the most well-known medications and other items we still use today, most notably, Celebrex, Ambien, Dramamine and NutraSweet. As you can see Searle developed some very important products over the years and its development of Oxandrolone is no exception because with its inception one of the safest anabolic steroids for both men and women would hit the shelves.
As a very mild anabolic steroid Oxandrolone is not well-suited for bulking cycles or gaining phases; you will not produce a vast amount of lean muscle tissue through its use when speaking of performance enhancing purposes; however, what is produced will be solid muscle tissue. The greatest benefits associated with this particular steroid lie within muscle preservation and metabolic activity.
This simply means Oxandrolone has the ability to not only aid in reducing body-fat but preserving muscle tissue while on a calorie restricted diet; further, the more muscle tissue we have the greater our metabolic activity will be thereby increasing the rate in-which body-fat is utilized for energy. Because Oxandrolone is apt for fat reduction and muscle preservation it is commonly used by physique athletes during their competition preparation, as well as by common gym rats who simply want to look leaner and tighter at the beach.
Most anabolic steroids carry with them the possibility of many adverse side-effects. It is important to keep in mind these side-effects are only possible, they are by no means guaranteed or assured and are largely avoidable when used responsibly.
However, negative side-effects can occur when steroids are abused and even in some who are sensitive even though they use responsibly they may fall prey to negative outcomes; the same can be said of Aspirin.
While many anabolic steroids carry vast possible negative side-effects such as estrogenic related due to aromatization, Oxandrolone does not possess these traits. Oxandrolone does not aromatize making common side-effects such as Gynecomastia little to no concern; Further, as most steroids are very suppressive to natural testosterone production Oxandrolone is very mild in this regard, so mild that one could take Oxandrolone and still produce some natural testosterone. However, some suppression will still exist and the extent will largely be dose dependent.
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